Sweet 16 point spreads, odds for each men’s NCAA tournament regional semifinal game

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With the first two rounds of the men’s basketball NCAA tournament complete, we’re down to the Sweet 16 for another year. Now, with a few days off before the next round, it’s time to look at some point spreads, money-line odds and over/unders for the regional semifinals.

It’s no surprise that the remaining No. 1 seeds, Alabama and Houston, are not only the national title favorites but also heavy chalk in their next matchup. The Crimson Tide is a 7.5-point favorite over No. 5 seed San Diego State in the South Region, while the Cougars are -7 against No. 5 Miami in the Midwest.

But the biggest favorite in the Sweet 16 is actually South No. 6 seed Creighton, which drew No. 15 seed Princeton and is favored by 9.5. But beware: Last season, No. 15 seed St. Peter’s beat No. 3 Purdue outright as a 13-point underdog.

Only one lower seed is favored. That’s Michigan State, which is 2-point chalk as the East No. 7 seed over No. 3 Kansas State.

Here is a complete list of lines and over/unders from Caesars Sportsbook:

Sweet 16 odds

(As of Tuesday morning; view updated lines here)


East Region: No. 7 Michigan State (-2, ML -135) vs. No. 3 Kansas State (ML +115, o/u 137.5), 6:30 p.m.

West Region: No. 4 UConn (-3.5, ML -165) vs. No. 8 Arkansas (ML +140, o/u 140), 7:15 p.m.

East Region: No. 4 Tennessee (-5.5, ML -240) vs. No. 9 Florida Atlantic (ML +195, o/u 130.5), 9 p.m.

West Region: No. 2 UCLA (-2, ML -135) vs. No. 3 Gonzaga (ML +115, o/u 145.5), 9:45 p.m.


South Region: No. 1 Alabama (-7.5, ML -355) vs. No. 5 San Diego State (ML +278, o/u 137), 6:30 p.m.

Midwest Region: No. 1 Houston (-7, ML -335) vs. No. 5 Miami (ML +260, o/u 138), 7:15 p.m.

South Region: No. 6 Creighton (-9.5, ML 480) vs. No. 15 Princeton (ML +360, o/u 140), 9 p.m.

Midwest Region: No. 2 Texas (-4, ML -180) vs. No. 3 Xavier (ML +152, o/u 148.5), 9:45 p.m.

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